Description

Bufexamac is a non-steroidal anti-inflammatory drug (NSAID) belonging to the class of para-alkoxyanilides, primarily recognized for its topical anti-inflammatory and analgesic properties. Its core value lies in its effective inhibition of cyclooxygenase (COX) enzymes, which reduces the production of prostaglandins, key mediators of inflammation and pain. This makes it a critical active pharmaceutical ingredient (API) for manufacturers developing topical formulations aimed at treating skin conditions and localized pain. Industries requiring this compound include pharmaceutical R&D, contract manufacturing organizations (CMOs), and producers of dermatological and veterinary medicinal products.

Application

• Topical Anti-inflammatory Preparations: Primary use as the active ingredient in creams, ointments, and gels for treating skin inflammation, eczema, and dermatitis.
• Analgesic Formulations: Incorporated into topical products designed for the relief of muscle aches, joint pain, and minor arthritis.
• Veterinary Medicine: Used in topical treatments for inflammatory conditions in animals.
• Pharmaceutical Intermediates: Serves as a key building block or intermediate in the synthesis of more complex therapeutic agents.
• Research & Development: Utilized in biochemical and pharmacological studies to investigate COX inhibition pathways and develop new NSAID derivatives.
• Cosmeceuticals: Potential use in specialized skincare products targeting redness and inflammation, under appropriate regulatory frameworks.

Basic Information

Product Name	Bufexamac
CAS No.	2438-89-3
Molecular Formula	C12H17NO3
Molecular Weight	223.27 g/mol
Synonyms	2-(4-Butoxyphenyl)-N-hydroxyacetamide; Butoxyphenyl acetohydroxamic acid; Bufexamic acid; BRN 2209731; Droxaryl; Flogocid; Paraderm; Parfenac
EINECS	219-439-3

Quality Control

Our Bufexamac is manufactured under a strict quality management system to ensure batch-to-batch consistency and reliability. We provide material that meets high-purity standards suitable for pharmaceutical applications, with typical purity levels exceeding 98.5% (HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles, ensuring compliance with relevant pharmacopeial guidelines and customer-specific requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.