Description

3-α-Hydroxy-6-Ketocholanic Acid is a high-purity bile acid derivative and a key intermediate in the synthesis of pharmaceutical compounds. This compound matters for its role as a critical building block in the development of therapeutic agents targeting metabolic and liver-related pathways. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of novel drugs, reference standards, and advanced biochemical studies.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of steroidal drugs and therapeutic bile acid analogs.
• Biochemical Research: Used as a reference standard and reagent in metabolic pathway studies and enzyme inhibition assays.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key starting material (KSM) or intermediate in the manufacture of complex APIs.
• Analytical Chemistry: Employed as a high-purity standard for calibration in chromatographic analysis (HPLC, LC-MS).
• Metabolite Studies: Utilized in research investigating bile acid metabolism and related disorders.

Basic Information

Product Name	3-α-Hydroxy-6-Ketocholanic Acid
CAS No.	2393-61-5
Molecular Formula	C24H38O5
Molecular Weight	406.56 g/mol
Synonyms	3α-Hydroxy-6-oxo-5β-cholan-24-oic Acid; 6-Ketolithocholic Acid; 3α-Hydroxy-6-keto-5β-cholanic Acid; 3α-Hydroxy-6-oxocholanic Acid; 6-Keto-3α-hydroxycholanic Acid; NSC 68393; Hyocholic Acid Metabolite
EINECS	Contact for details

Quality Control

Our 3-α-Hydroxy-6-Ketocholanic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets high-purity standards suitable for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.