Description

α-Muricholic Acid is a primary bile acid and a significant metabolite of chenodeoxycholic acid. This compound is of critical importance in biochemical research for studying bile acid metabolism, transport, and signaling pathways. It is primarily utilized by researchers and manufacturers in the pharmaceutical and life science sectors for developing analytical standards, investigating liver function, and exploring therapeutic applications related to cholestatic and metabolic disorders.

Application

• Biochemical Research Standard: Serves as a high-purity reference standard for analytical methods such as HPLC and LC-MS in the quantification of bile acids.
• Metabolic Pathway Studies: Used in laboratory research to investigate the biosynthesis, conjugation, and enterohepatic circulation of bile acids.
• Pharmacology & Drug Discovery: Employed in studies targeting nuclear receptors like FXR (Farnesoid X receptor) and TGR5 for potential therapies in liver and metabolic diseases.
• Cell Culture & In Vitro Assays: Applied in cell-based studies to examine the effects of bile acids on cell viability, inflammation, and apoptosis.
• Diagnostic Development: Utilized in the development and calibration of diagnostic kits and assays for detecting bile acid disorders.

Basic Information

Product Name	α-Muricholic Acid
CAS No.	2393-58-0
Molecular Formula	C₂₄H₄₀O₅
Molecular Weight	408.57 g/mol
Synonyms	3α,6β,7α-Trihydroxy-5β-cholan-24-oic Acid; Muricholic Acid; α-Muricholate; 5β-Cholan-24-oic acid, 3α,6β,7α-trihydroxy-, (3α,5β,6β,7α)-; Hyocholic Acid (related isomer); 3α,6β,7α-Trihydroxycholanoic Acid
EINECS	Contact for details

Quality Control

Our α-Muricholic Acid is produced and tested under strict quality management systems. Each batch undergoes comprehensive analytical characterization, including HPLC for purity assessment and spectroscopic methods for structural confirmation, to ensure it meets the high standards required for research applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at 2-8°C. The product is hygroscopic (moisture-sensitive). For long-term storage, consider desiccation or storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.