Description

1,4-Dichlorophthalazine-6-Carbonyl Chloride is a versatile and highly reactive organic intermediate characterized by its dual acid chloride and halogenated heterocyclic structure. This compound is essential for the efficient synthesis of complex molecules, enabling the rapid introduction of the phthalazine pharmacophore and facilitating further functionalization. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of phthalazine-based drug candidates, particularly in oncology and CNS research.
• Agrochemical Synthesis: Used in the development of novel herbicides and pesticides, leveraging its heterocyclic core.
• Material Science Research: Serves as a precursor for creating specialized polymers and ligands with unique electronic properties.
• Chemical Biology Probes: Utilized in the design of activity-based probes and molecular tags for studying enzyme function.
• Dye and Pigment Intermediate: Acts as a starting material for synthesizing complex heterocyclic dyes and colorants.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	1,4-Dichlorophthalazine-6-Carbonyl Chloride
CAS No.	2380-50-9
Molecular Formula	C9H3Cl3N2O
Molecular Weight	261.49 g/mol
Synonyms	6-(Chlorocarbonyl)-1,4-dichlorophthalazine; 1,4-Dichloro-6-phthalazinecarbonyl chloride; 1,4-Dichlorophthalazine-6-carboxylic acid chloride; Phthalazine-6-carbonyl chloride, 1,4-dichloro-; 2380-50-9; 1,4-Dichloro-6-carboxyphthalazine chloride
EINECS	Contact for details

Quality Control

Our production of 1,4-Dichlorophthalazine-6-Carbonyl Chloride adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed using advanced techniques including HPLC, NMR, and FT-IR to confirm identity and purity. Certificates of Analysis (COA) detailing all relevant specifications are provided with every shipment and are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Solubility	Soluble in common organic solvents (DMF, THF, DCM)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.