Description

1-(2-Fluorophenyl)-2-Propyn-1-Ol is a versatile fluorinated propargylic alcohol building block. This compound is valued for its unique molecular structure, which combines a fluorinated aromatic ring with a reactive terminal alkyne and a hydroxyl group, enabling diverse synthetic transformations. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for the synthesis of complex molecules and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key synthon for constructing fluorinated drug candidates, including kinase inhibitors and CNS-active compounds.
• Agrochemical Research: Used in the development of novel herbicides and pesticides where the fluorine atom enhances biological activity and metabolic stability.
• Material Science: Serves as a monomer or cross-linking agent in the synthesis of specialty polymers and advanced resins.
• Organic Synthesis: Employed in click chemistry reactions, Sonogashira couplings, and other palladium-catalyzed cross-coupling processes.
• Ligand & Catalyst Development: Useful for preparing chiral ligands and organocatalysts for asymmetric synthesis.
• Fluorine Chemistry Studies: Acts as a model substrate for investigating the electronic effects of ortho-fluorine substitution on aromatic systems.

Basic Information

Product Name	1-(2-Fluorophenyl)-2-Propyn-1-Ol
CAS No.	2343-61-5
Molecular Formula	C9H7FO
Molecular Weight	150.15 g/mol
Synonyms	2-Fluorophenyl propargyl alcohol; (2-Fluorophenyl)(prop-2-yn-1-yl) alcohol; 1-(2-Fluorophenyl)prop-2-yn-1-ol; 2-Fluorobenzeneethanol, β-ethynyl-; α-Ethynyl-2-fluorobenzyl alcohol; Propargyl alcohol, 2-fluorophenyl-; 2-Fluorophenylacetylene carbinol
EINECS	Contact for details

Quality Control

Our 1-(2-Fluorophenyl)-2-Propyn-1-Ol is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with every shipment, confirming compliance with customer specifications and industry best practices for fine chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.