Description

3,3,3-Trifluoro-1-Phenylpropan-1-Ol is a versatile fluorinated aromatic alcohol that serves as a critical chiral building block in advanced organic synthesis. Its unique structure, featuring a trifluoromethyl group adjacent to a chiral secondary alcohol, makes it a valuable intermediate for introducing fluorine atoms into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients with enhanced metabolic stability, bioavailability, and lipophilicity.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in CNS and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where the trifluoromethyl group improves efficacy and environmental profile.
• Liquid Crystal Materials: Serves as a precursor for fluorinated components in liquid crystal displays (LCDs) to optimize dielectric anisotropy and viscosity.
• Advanced Material Science: Building block for specialty polymers and coatings where fluorine incorporation enhances chemical resistance, thermal stability, and surface properties.
• Asymmetric Catalysis Research: Valuable substrate for testing and developing new chiral catalysts and methodologies in academic and industrial R&D settings.
• Fluorine Chemistry Reference Standard: Used as a pure standard for analytical method development and quality control in fluorochemical production.

Basic Information

Product Name	3,3,3-Trifluoro-1-Phenylpropan-1-Ol
CAS No.	2340-22-9
Molecular Formula	C9H9F3O
Molecular Weight	190.16 g/mol
Synonyms	α-(Trifluoromethyl)benzenemethanol; 1-Phenyl-3,3,3-trifluoropropan-1-ol; (RS)-3,3,3-Trifluoro-1-phenyl-1-propanol; 3,3,3-Trifluoro-1-phenylpropanol; Benzenemethanol, α-(trifluoromethyl)-; (±)-3,3,3-Trifluoro-1-phenyl-1-propanol; 3,3,3-Trifluoro-1-phenylethyl carbinol
EINECS	219-052-7

Quality Control

Our 3,3,3-Trifluoro-1-Phenylpropan-1-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity assessment, to ensure it meets the exacting standards required for advanced synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting purity, enantiomeric excess (where applicable), and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and bases.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Purity (GC/HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.