Description

5α-Androstan-1α-Ol CAS NO 2287-84-5 is a high-purity steroid derivative and a key intermediate in organic synthesis. This compound is valued for its defined stereochemistry, which is critical for producing specific bioactive molecules and reference standards. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in steroid chemistry, hormone research, and the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of more complex steroid-based active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing.
• Biochemical Research: Serves as a precursor or model compound in metabolic pathway studies, receptor binding assays, and endocrinology research.
• Organic Synthesis: Employed in stereoselective synthesis to construct molecules with specific chiral centers, leveraging its 1α-hydroxy-5α-androstane skeleton.
• Metabolite Standard: Used in the identification and quantification of steroid metabolites in clinical and forensic toxicology.

Basic Information

Product Name	5α-Androstan-1α-Ol
CAS No.	2287-84-5
Molecular Formula	C₁₉H₃₂O
Molecular Weight	276.46 g/mol
Synonyms	1α-Hydroxy-5α-androstane; 5α-Androstan-1α-ol; 1α-Hydroxyandrostane; Androstan-1α-ol; 1α-Hydroxy-5α-androstan-3-one (related ketone); 1α-OH-5α-Androstane; 5α-Androstane-1α-ol; 1α-Hydroxyetioallocholane
EINECS	Contact for details

Quality Control

Our 5α-Androstan-1α-Ol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and specific tests for residual solvents and related substances. We provide Certificates of Analysis (COA) with detailed chromatographic data and full traceability to ensure compliance with research and pharmaceutical intermediate standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.