Description

n-4-Hydroxy-2'-Deoxycytidylic Acid is a modified nucleoside monophosphate of significant interest in biochemical and pharmaceutical research. This compound serves as a critical building block and a key intermediate in the synthesis of oligonucleotides and nucleotide analogs. It is primarily utilized by researchers and manufacturers in the fields of antiviral drug development, cancer research, and molecular biology for studying DNA repair mechanisms and enzyme interactions.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving DNA polymerases and nucleotidyl transferases.
• Oligonucleotide Synthesis: Serves as a modified building block for constructing DNA strands with specific functionalities for diagnostic and therapeutic applications.
• Proteomics & Genomics: Employed in research tools and kits for studying DNA damage, repair pathways, and epigenetic modifications.
• Reference Standard: Used as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	n-4-Hydroxy-2'-Deoxycytidylic Acid
CAS No.	2277-58-9
Molecular Formula	C9H13N3O7P
Molecular Weight	306.19 g/mol
Synonyms	4-Hydroxy-2'-deoxycytidine 5'-monophosphate; 4-OH-dCMP; 5'-dCMP-4-ol; 2'-Deoxy-4-hydroxycytidine 5'-monophosphate; Hydroxymethyldeoxycytidine monophosphate; 4-Hydroxy-2'-deoxycytidylic acid; 4-Hydroxy-dCMP; 4-OH-2'-Deoxycytidine-5'-monophosphate
EINECS	Contact for details

Quality Control

Our n-4-Hydroxy-2'-Deoxycytidylic Acid is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and pharmaceutical applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. For long-term storage, consider desiccant and under inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/IR)	Conforms to reference standard
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.