Description

3-Methylbenzofuran-2-Carbonyl Chloride is a versatile and highly reactive organic intermediate, specifically an acid chloride derivative of a benzofuran carboxylic acid. Its core value proposition lies in its ability to efficiently introduce the 3-methylbenzofuran-2-carbonyl moiety into more complex molecular architectures through amidation or esterification reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries who require a reliable building block for the synthesis of novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and insecticides, leveraging the benzofuran scaffold's bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the development of advanced polymers and organic electronic materials.
• Ligand and Catalyst Development: Employed to create specialized ligands for metal complexes used in asymmetric catalysis and other synthetic transformations.
• Fluorescent Probe and Dye Chemistry: Acts as a building block for synthesizing benzofuran-based fluorophores and chromophores used in imaging and sensing applications.
• Custom Synthesis and Contract Manufacturing: A critical reagent for fine chemical manufacturers offering bespoke synthesis services to the life sciences sector.

Basic Information

Product Name	3-Methylbenzofuran-2-Carbonyl Chloride
CAS No.	2256-86-2
Molecular Formula	C11H7ClO2
Molecular Weight	206.62 g/mol
Synonyms	2-(Chlorocarbonyl)-3-methylbenzofuran; 3-Methyl-2-benzofurancarbonyl chloride; 3-Methylbenzofuran-2-carboxylic acid chloride; 3-Methyl-2-benzofuranyl carbonyl chloride; 3-Methylbenzo[b]furan-2-carbonyl chloride; 2-Carboxy-3-methylbenzofuran chloride; α-Oxo-3-methyl-2-benzofuranacetyl chloride (obsolete)
EINECS	Contact for details

Quality Control

Every batch of 3-Methylbenzofuran-2-Carbonyl Chloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic and moisture-sensitive nature, the container should be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Recommended storage temperature is 2-8°C for long-term stability.

Specification

Item	Specification
Appearance	White to off-white crystalline solid or powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.