Description

Pentafluorobenzoyl Chloride is a highly reactive and versatile fluorinated aromatic acid chloride. Its primary value lies in its role as a key fluorinated building block for introducing the pentafluorophenyl moiety into target molecules, which can dramatically alter their physical, chemical, and biological properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorination to develop new active ingredients, ligands, or specialty polymers.

Application

• Pharmaceutical Intermediate: Critical for synthesizing active pharmaceutical ingredients (APIs) and diagnostic agents where fluorination enhances metabolic stability, bioavailability, and membrane permeability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, where the pentafluorophenyl group can improve efficacy and environmental profile.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in catalysis and metal-organic frameworks (MOFs).
• Derivatization Agent for Analytics: Employed in gas chromatography (GC) and liquid chromatography (LC) to derivative compounds for improved detection and separation.
• Polymer and Material Science: Incorporated into polymer backbones or as a surface modifier to impart unique properties like hydrophobicity, chemical resistance, or low surface energy.
• Organic Synthesis Building Block: Used in amidation and esterification reactions to create a wide array of pentafluorobenzoyl derivatives for research and development.

Basic Information

Product Name	Pentafluorobenzoyl Chloride
CAS No.	2251-50-5
Molecular Formula	C7ClF5O
Molecular Weight	230.52 g/mol
Synonyms	2,3,4,5,6-Pentafluorobenzoyl chloride; Perfluorobenzoyl chloride; Pentafluorobenzoic acid chloride; Benzoyl chloride, pentafluoro-; Pentafluorobenzoic chloride; PFBC; Pentafluorobenzoylchloride; 2251-50-5
EINECS	218-837-3

Quality Control

Our Pentafluorobenzoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and moisture.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.