Description

[[[[(2S,3S,4R,5R)-5-(4-Amino-2-Oxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Amino]Oxy-Hydroxy-Phosphoryl]Oxy-Hydroxy-Phosphoryl]Oxyphosphonic Acid is a high-purity nucleotide analog of significant interest in advanced biochemical research and pharmaceutical development. This compound serves as a critical building block and research tool for studying enzymatic pathways, nucleic acid metabolism, and antiviral mechanisms. It is essential for researchers and manufacturers in the fields of nucleoside chemistry, prodrug synthesis, and targeted therapeutic development. The consistent quality and reliable supply of this material are paramount for ensuring reproducible experimental and production outcomes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside prodrugs.
• Biochemical Research: Essential tool for studying the activity of kinases, polymerases, and other enzymes involved in nucleotide metabolism.
• Proteomics & Molecular Biology: Used in the development of probes and substrates for investigating protein-nucleic acid interactions and signaling pathways.
• Antiviral Agent Development: Serves as a core scaffold for creating compounds that target viral replication mechanisms.
• Diagnostic Reagent Manufacturing: Component in the production of specialized reagents for molecular diagnostics and assay kits.
• Academic & Institutional Research: Critical material for universities and research institutes conducting fundamental studies in medicinal chemistry and biochemistry.

Basic Information

Product Name	[[[[(2S,3S,4R,5R)-5-(4-Amino-2-Oxo-Pyrimidin-1-Yl)-3,4-Dihydroxy-Oxolan-2-Yl]Amino]Oxy-Hydroxy-Phosphoryl]Oxy-Hydroxy-Phosphoryl]Oxyphosphonic Acid
CAS No.	2226-74-6
Molecular Formula	C9H16N4O14P3
Molecular Weight	497.16 g/mol
Synonyms	2'-Deoxycytidine-5'-triphosphate (dCTP) analog; Cytidine nucleotide triphosphate derivative; 5'-O-[Hydroxy(phosphonooxy)phosphoryl]-2'-deoxycytidine 3'-(dihydrogen phosphate); dCTP α,β,γ-trivalent analog; Nucleoside triphosphate mimic; 2'-Deoxycytidine 5'-(tetrahydrogen triphosphate); P1,P3-Di(2'-deoxycytidin-5'-yl) triphosphate; Research Compound 2226-74-6
EINECS	Contact for details

Quality Control

Our production of this nucleotide analog adheres to stringent quality management protocols to ensure batch-to-batch consistency and purity suitable for sensitive research and development applications. Quality is verified through a comprehensive suite of analytical techniques including HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA), providing full characterization and purity data, is supplied with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to minimize condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines
Biological Activity	Assay dependent (available)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.