Description

(3S,5S,8R,9S,10S,13S,14S,16R,17S)-17-(1-Hydroxyethyl)-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthrene-3,16-Diol is a high-purity, stereochemically defined steroid derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical intermediate or reference standard for synthesizing novel therapeutic agents, particularly in the fields of endocrinology and anti-inflammatory drug discovery. It is essential for research institutions, pharmaceutical R&D departments, and fine chemical manufacturers requiring precise molecular building blocks with guaranteed stereochemical integrity.

Application

• Pharmaceutical Intermediate: Key starting material or advanced intermediate in the synthesis of novel steroid-based therapeutics targeting hormone receptors.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control of related steroid compounds via HPLC, GC-MS, or NMR.
• Biochemical Research: Tool compound for studying steroid biosynthesis pathways, enzyme inhibition, and receptor-ligand interactions in vitro.
• Process Chemistry: Employed in route scouting and optimization for the commercial-scale production of complex steroid molecules.
• Academic Research: Serves as a substrate or model compound in university and institutional research exploring new organic synthetic methodologies.

Basic Information

Product Name	(3S,5S,8R,9S,10S,13S,14S,16R,17S)-17-(1-Hydroxyethyl)-10,13-Dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-Tetradecahydro-1H-Cyclopenta[A]Phenanthrene-3,16-Diol
CAS No.	2220-64-6
Molecular Formula	C₂₁H₃₄O₃
Molecular Weight	334.49 g/mol
Synonyms	3β,16β-Dihydroxy-5β-androstane-17β-ethanol; 17β-(1-Hydroxyethyl)-5β-androstane-3β,16β-diol; 5β-Androstane-3β,16β,17β-triol, 17β-ethyl derivative; Androstane triol derivative; Steroid diol intermediate; (3β,5β,16β,17β)-17-(1-Hydroxyethyl)-androstane-3,16-diol
EINECS	Contact for details

Quality Control

Every batch of our steroid intermediates is produced and tested under a strict quality management system. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles, typically determined by advanced chromatographic methods (HPLC, GC) and spectroscopic techniques (NMR, IR). Our commitment to traceability and consistency ensures the material meets the exacting requirements for pharmaceutical R&D and process development. Specifications can be aligned with client-specific pharmacopeial or internal standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.