Description

20-Hydroxy-4,8,14-Trimethyl-4-Methylene-18-Nor-3,4-Seco-5β-Cholane-3,24-Dioic Acid γ-Lactone is a high-purity steroidal lactone derivative, valued for its role as a critical synthetic intermediate and reference standard in advanced pharmaceutical research. This compound matters for its structural complexity and utility in the synthesis of bioactive molecules and for analytical method development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical sectors working on steroid-based therapeutics and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key building block in the multi-step synthesis of complex steroidal drugs and bioactive compounds.
• Reference Standard: Used for quality control, method validation, and calibration in analytical laboratories (HPLC, GC-MS, NMR).
• Biochemical Research: Serves as a precursor or model compound in studies of steroid biosynthesis, metabolism, and receptor interactions.
• Process Chemistry: Employed in route scouting and optimization for the scalable production of target molecules.
• Academic Research: Utilized in universities and research institutes for exploring new chemical reactions and synthesizing novel derivatives.
• Fine Chemical Synthesis: A specialized starting material for creating high-value, custom-synthesized chemicals for various industrial applications.

Basic Information

Product Name	20-Hydroxy-4,8,14-Trimethyl-4-Methylene-18-Nor-3,4-Seco-5β-Cholane-3,24-Dioic Acid γ-Lactone
CAS No.	2202-01-9
Molecular Formula	C₂₇H₄₀O₄
Molecular Weight	428.61 g/mol
Synonyms	3,24-Dinor-5β-cholan-3,24-dioic acid, 4,8,14-trimethyl-4-methylene-18-nor-3,4-seco-, γ-lactone, 20-hydroxy-; 20-Hydroxy-4,8,14-trimethyl-4-methylene-18-nor-3,4-seco-5β-cholane-3,24-dioic acid γ-lactone; 3,24-Dinor-5β-cholan-3,24-dioic acid, 20-hydroxy-4,8,14-trimethyl-4-methylene-18-nor-3,4-seco-, γ-lactone; 4,8,14-Trimethyl-4-methylene-18-nor-3,4-seco-5β-cholane-3,24-dioic acid γ-lactone, 20-hydroxy-; Steroidal Lactone Derivative (2202-01-9)
EINECS	Contact for details

Quality Control

Our 20-Hydroxy-4,8,14-Trimethyl-4-Methylene-18-Nor-3,4-Seco-5β-Cholane-3,24-Dioic Acid γ-Lactone is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and spectroscopic methods (NMR, IR, MS) for structural confirmation, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.