Description

Ropivacaine-Et is a key pharmaceutical intermediate and reference standard, specifically the ethyl derivative of the widely used local anesthetic Ropivacaine. This compound is critical for research, development, and quality control processes in the synthesis of enantiomerically pure anesthetic agents. It serves the essential needs of pharmaceutical R&D laboratories, analytical testing facilities, and fine chemical manufacturers focused on central nervous system (CNS) active ingredients and chiral chemistry.

Application

• Pharmaceutical Intermediate: Primary building block in the synthesis of Ropivacaine and its structural analogs.
• Analytical Reference Standard: Used for method development, validation, and quality control (HPLC, GC, LC-MS) in pharmaceutical analysis.
• Metabolite Studies: Employed in pharmacokinetic and metabolic pathway research for anesthetic drugs.
• Process Chemistry & Impurity Profiling: Essential for identifying and quantifying process-related impurities in Ropivacaine API manufacturing.
• Chiral Chemistry Research: A valuable compound for studying stereoselective synthesis and the effects of enantiomeric purity.
• Academic & Institutional Research: Used in universities and research institutes for pharmacological and medicinal chemistry studies.

Basic Information

Product Name	Ropivacaine-Et
CAS No.	2180-94-1
Molecular Formula	C18H28N2O
Molecular Weight	288.43 g/mol
Synonyms	(S)-N-(2,6-Dimethylphenyl)-1-propylpiperidine-2-carboxamide; (S)-1-Propyl-2',6'-pipecoloxylidide; (S)-1-Propyl-2',6'-pipecoloxylidide Ethyl Derivative; Ropivacaine Ethyl Analog; Ropivacaine Related Compound; LEVA-1249; (2S)-N-(2,6-Dimethylphenyl)-1-propyl-2-piperidinecarboxamide
EINECS	Contact for details

Quality Control

Our Ropivacaine-Et is produced under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including identity confirmation by IR and NMR, purity assessment by HPLC, and control of specific impurities. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing the results against agreed specifications. Our quality commitment ensures material suitable for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed after opening to minimize exposure to atmospheric moisture. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.