Description

Bupivacaine is a potent, long-acting amide-type local anesthetic widely used in medical and pharmaceutical applications. Its primary value lies in providing extended regional anesthesia and analgesia, making it a critical component in surgical and pain management protocols. This compound is essential for pharmaceutical manufacturers, research institutions, and compounding pharmacies involved in producing injectable formulations for nerve blocks, epidural anesthesia, and postoperative pain relief. Bupivacaine CAS NO 2180-92-9 is supplied under stringent quality control to ensure purity and efficacy for sensitive end-uses.

Application

• Pharmaceutical Active Ingredient (API): Primary use in the manufacture of injectable local anesthetic solutions for medical and surgical applications.
• Regional Anesthesia: Formulated for epidural blocks, spinal anesthesia, and peripheral nerve blocks in hospital and clinical settings.
• Postoperative Pain Management: Used in extended-release formulations for controlling pain following surgical procedures.
• Veterinary Medicine: Employed in anesthetic and analgesic preparations for animal healthcare.
• Research & Development: Serves as a reference standard and key intermediate in pharmacological studies and new drug development.
• Compounding Pharmacies: Used in the preparation of customized anesthetic solutions tailored to specific patient needs.

Basic Information

Item	Detail
Product Name	Bupivacaine
CAS No.	2180-92-9
Molecular Formula	C18H28N2O
Molecular Weight	288.43 g/mol
Synonyms	1-Butyl-N-(2,6-dimethylphenyl)piperidine-2-carboxamide; (±)-Bupivacaine; Bupivacaine Hydrochloride (salt form); Marcaine; Sensorcaine; Bupivacaine Base; Bupivacaine Free Base; DL-Bupivacaine
EINECS	218-553-4

Quality Control

Our Bupivacaine is manufactured and tested to meet high-purity standards suitable for pharmaceutical applications. Quality assurance protocols align with ICH guidelines and current industry best practices. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to ensure full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Optical Rotation	-0.10° to +0.10° (for specific enantiomer grades)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.