Description

6-Azauridine 2',3',5'-Triacetate is a chemically modified nucleoside analog, specifically the triacetylated derivative of 6-azauridine. This compound is a crucial intermediate in organic synthesis and pharmaceutical research, valued for its role in modifying nucleoside structures to alter their biological activity and pharmacokinetic properties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for the development of antiviral and anticancer agents, as well as for biochemical studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Antiviral Agent Development: Serves as a precursor for compounds targeting viral replication mechanisms, particularly for RNA viruses.
• Prodrug Synthesis: The acetyl groups provide a protective strategy, making it a valuable intermediate for creating more bioavailable prodrug forms of active nucleoside analogs.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.
• Organic Synthesis: Used in academic and industrial research for the chemical modification of sugar moieties in nucleoside chemistry.

Basic Information

Product Name	6-Azauridine 2',3',5'-Triacetate
CAS No.	2169-64-4
Molecular Formula	C14H17N3O9
Molecular Weight	371.30 g/mol
Synonyms	6-Azauracil riboside triacetate; 2',3',5'-Tri-O-acetyl-6-azauridine; 6-Azauridine triacetate; 1-((2R,3R,4R,5R)-3,4-Diacetoxy-5-(acetoxymethyl)tetrahydrofuran-2-yl)-1,2,4-triazine-3,5(2H,4H)-dione; 6-AZU triacetate; NSC 32074; 6-Aza-2',3',5'-tri-O-acetyluridine
EINECS	Contact for details

Quality Control

Our 6-Azauridine 2',3',5'-Triacetate is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a Certificate of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Specific Rotation	Contact for details
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.