Description

Pipazethate CAS NO 2167-85-3 is a synthetic compound belonging to the class of piperazine derivatives, recognized for its specific pharmacological activity. This high-purity active pharmaceutical ingredient (API) is critical for ensuring the efficacy and consistency of finished pharmaceutical formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of therapeutic agents.

Application

• Pharmaceutical API: Serves as the key active ingredient in the formulation of antitussive (cough suppressant) medications.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for quality control and method validation.
• Pharmacological Research: Employed in preclinical and clinical studies to investigate mechanisms of action and therapeutic efficacy.
• Drug Development: A crucial intermediate or final compound in the R&D pipeline for new respiratory and central nervous system (CNS) related therapies.
• Generic Drug Manufacturing: Essential for producing bioequivalent generic versions of established cough suppressant drugs.

Basic Information

Product Name	Pipazethate
CAS No.	2167-85-3
Molecular Formula	C21H27ClN2O3
Molecular Weight	390.91 g/mol
Synonyms	Pipazetate; Selvigon; Theratuss; 2-(2-Piperidinoethoxy)ethyl 10H-pyrido[3,2-b][1,4]benzothiazine-10-carboxylate; 10H-Pyrido[3,2-b][1,4]benzothiazine-10-carboxylic acid 2-(2-piperidinoethoxy)ethyl ester; Piperazethate; Tussafug
EINECS	218-504-9

Quality Control

Our Pipazethate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A detailed Certificate of Analysis (COA) providing results for assay, related substances, residual solvents, and other critical parameters is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water (KF)	≤ 1.0% w/w
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.