Description

5-Aminouridine is a modified nucleoside derivative of uridine, where an amino group replaces the hydroxyl group at the 5-position of the pyrimidine ring. This structural modification makes it a valuable building block and intermediate in the synthesis of more complex nucleoside analogs and oligonucleotides. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery, nucleic acid chemistry, and biochemical research.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel antiviral and anticancer nucleoside drugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to nucleotide metabolism and RNA biology.
• Oligonucleotide Synthesis: Serves as a modified monomer for incorporating specific functionalities into synthetic DNA or RNA strands.
• Probe Development: Useful for creating labeled nucleosides for diagnostic assays and molecular imaging.
• Academic Research: Employed in studies investigating nucleic acid structure, function, and chemical modification.

Basic Information

Product Name	5-Aminouridine
CAS No.	2149-76-0
Molecular Formula	C9H13N3O6
Molecular Weight	259.22 g/mol
Synonyms	5-Amino-1-β-D-ribofuranosyluracil; 5-Amino-1-β-D-ribofuranosyl-2,4(1H,3H)-pyrimidinedione; 5-Amino-uridine; 5-Amino-Urd; 5-AU; 1-(β-D-Ribofuranosyl)-5-aminouracil
EINECS	218-417-9

Quality Control

Our 5-Aminouridine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.