Description

1-Methylinosine is a modified nucleoside derivative of inosine, where a methyl group is attached to the N1 position of the purine ring. This specific structural modification makes it a valuable intermediate and reference standard in advanced biochemical research and pharmaceutical development. It is primarily utilized by research institutions and manufacturers in the life sciences sector for applications in nucleotide chemistry, antiviral studies, and as a building block for more complex molecular entities. Our supply ensures high purity and batch-to-batch consistency critical for sensitive experimental and production workflows.

Application

• Pharmaceutical Intermediate: Serves as a key synthetic precursor in the development of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a reference standard and substrate in enzymatic studies, particularly those involving purine metabolism and nucleoside-modifying enzymes.
• Nucleotide Chemistry: Acts as a building block for the synthesis of modified oligonucleotides for diagnostic and therapeutic applications.
• Antiviral Agent Development: Investigated for its potential role and mechanism in the research of RNA virus inhibition.
• Cell Culture & Media Supplements: May be used as a specialized component in cell culture media for specific metabolic studies.
• Enzyme Inhibitor Studies: Employed in research to study the inhibition of enzymes like purine nucleoside phosphorylase.

Basic Information

Product Name	1-Methylinosine
CAS No.	2140-73-0
Molecular Formula	C11H14N4O5
Molecular Weight	282.25 g/mol
Synonyms	1-Methylinosine; 1-Methyl-9H-purin-6(1H)-one riboside; 1-Methyl-9-β-D-ribofuranosylhypoxanthine; N1-Methylinosine; 1-Methyl-6-oxopurine riboside; Inosine, 1-methyl-; 9-β-D-Ribofuranosyl-1-methylhypoxanthine
EINECS	218-376-3

Quality Control

Our 1-Methylinosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity biochemical standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is sealed tightly after each use to prevent degradation due to moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.