Description

3-Methyl Uridine is a modified nucleoside where a methyl group is introduced at the 3-position of the uridine base. This structural modification is crucial for research in nucleic acid chemistry and drug discovery, as it can alter base-pairing properties and metabolic stability. It serves as a key building block and intermediate for pharmaceutical companies and research institutions developing nucleoside-based therapeutics, diagnostic probes, and biochemical tools.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used in studies of RNA structure, function, and modification (epitranscriptomics).
• Probe Development: Incorporated into oligonucleotides to study nucleic acid-protein interactions and enzyme mechanisms.
• Medicinal Chemistry: Serves as a scaffold for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Diagnostic Reagents: Potential use in the development of labeled nucleotides for detection assays.
• Academic & Industrial R&D: Fundamental research material in chemistry and biology laboratories for exploring nucleotide chemistry.

Basic Information

Product Name	3-Methyl Uridine
CAS No.	2140-69-4
Molecular Formula	C10H14N2O6
Molecular Weight	258.23 g/mol
Synonyms	3-Methyluridine; 3-Methyl-U; 1-((2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl)-3-methylpyrimidine-2,4-dione; 3-Methyl-1-β-D-ribofuranosyluracil; N3-Methyluridine; 3-Methyl-1-(β-D-ribofuranosyl)uracil
EINECS	218-378-5

Quality Control

Our 3-Methyl Uridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopy (NMR, IR). We provide Certificates of Analysis (COA) with detailed specifications for trace impurities, residual solvents, and assay value. Our quality commitment ensures material consistency for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a desiccated environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.