Description

5'-o-Acetyl Adenosine is a key acetylated derivative of the nucleoside adenosine, serving as a vital building block in organic synthesis and pharmaceutical research. Its primary value lies in its role as a protected intermediate, enabling the precise construction of more complex nucleotide analogs and oligonucleotides. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and life science sectors, particularly those developing antiviral agents, anticancer drugs, and novel therapeutic oligonucleotides.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of novel nucleoside-based antiviral and anticancer therapeutics.
• Oligonucleotide Synthesis: Used as a protected monomer in the solid-phase synthesis of DNA and RNA analogs for research and therapeutic applications.
• Biochemical Research: Serves as a substrate or inhibitor in enzymatic studies to understand nucleotide metabolism and related pathways.
• Prodrug Development: The acetyl group can be utilized in prodrug strategies to enhance the bioavailability and delivery of adenosine-based active pharmaceutical ingredients (APIs).
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	5'-o-Acetyl Adenosine
CAS No.	2140-25-2
Molecular Formula	C12H15N5O5
Molecular Weight	309.28 g/mol
Synonyms	Adenosine, 5'-acetate; 5'-Acetyladenosine; N6-(5'-O-Acetyl-β-D-ribofuranosyl)adenine; 9-β-D-Ribofuranosyladenine 5'-acetate; 5'-O-Acetyl-9-β-D-ribofuranosyladenine; 5'-Acetoxyadenosine; Adenosine 5'-acetate
EINECS	218-375-6

Quality Control

Our 5'-o-Acetyl Adenosine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide Certificates of Analysis (COA) with every shipment, detailing all specifications and test results to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.