Description

3-Carboxyphenyl Isothiocyanate is a versatile bifunctional organic compound that serves as a critical building block in advanced chemical synthesis. Its unique structure, featuring both an isothiocyanate group and a carboxylic acid moiety, makes it an invaluable reagent for creating complex molecules with tailored properties. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries, where it is used to develop active ingredients, functional polymers, and specialized chemical probes.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly for creating urea and thiourea derivatives with potential biological activity.
• Agrochemical Synthesis: Building block for developing new herbicides, fungicides, and plant growth regulators by incorporating the phenyl isothiocyanate scaffold.
• Polymer Modification: Used to introduce reactive functional groups into polymer chains, enabling the creation of specialty resins, coatings, and adhesives with enhanced properties.
• Bioconjugation & Labeling Reagent: Facilitates the covalent attachment of probes, tags, or drugs to biomolecules (proteins, peptides) via reaction with amine groups.
• Chemical Research & Development: Serves as a versatile starting material in organic synthesis for constructing heterocyclic compounds and complex molecular architectures.
• Material Science: Employed in the surface functionalization of nanoparticles and other nanomaterials to alter their chemical reactivity and compatibility.

Basic Information

Product Name	3-Carboxyphenyl Isothiocyanate
CAS No.	2131-63-7
Molecular Formula	C8H5NO2S
Molecular Weight	179.20 g/mol
Synonyms	3-Isothiocyanatobenzoic Acid; m-Carboxyphenyl Isothiocyanate; Benzoic acid, 3-isothiocyanato-; Isocyanic acid, 3-carboxyphenyl ester; 3-(Isothiocyanato)benzoic Acid; m-Isothiocyanatobenzoic Acid; NSC 401579
EINECS	218-366-9

Quality Control

Our 3-Carboxyphenyl Isothiocyanate is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.