Description

8-Chloroguanosine is a halogenated nucleoside derivative of guanosine, where a chlorine atom is substituted at the 8-position of the purine ring. This structural modification makes it a valuable intermediate and building block in organic synthesis and pharmaceutical research. It is primarily utilized by researchers and manufacturers in the life sciences sector for developing novel therapeutic agents and biochemical probes.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of antiviral and anticancer nucleoside analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate purine metabolism and related pathways.
• Organic Synthesis: Acts as a versatile building block for the chemical modification of nucleosides to create novel compounds with tailored properties.
• Probe Development: Utilized in the synthesis of labeled compounds or molecular probes for diagnostic and research applications.
• Academic & Industrial R&D: Employed in laboratories for fundamental research in medicinal chemistry and chemical biology.

Basic Information

Product Name	8-Chloroguanosine
CAS No.	2104-68-9
Molecular Formula	C10H12ClN5O5
Molecular Weight	317.69 g/mol
Synonyms	8-Chloro-guanosine; Guanosine, 8-chloro-; 8-Cl-Guanosine; 8-Chloro-9H-purin-6-amine, 9-β-D-ribofuranosyl-; 8-Chloroguanosine, 98+%; 8-Chloro-9-(β-D-ribofuranosyl)guanine; 8-Chloro-9-ribofuranosylguanine
EINECS	218-267-5

Quality Control

Our 8-Chloroguanosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.