Description

Gougerotin is a nucleoside antibiotic originally isolated from *Streptomyces gougerotii*. This compound is a valuable biochemical tool and research chemical due to its specific mechanism of action as a protein synthesis inhibitor. It is primarily utilized in life science research, particularly in studies of ribosomal function, antibiotic mechanisms, and cellular translation processes. Our high-purity grade ensures reliable and reproducible results for critical laboratory applications.

Application

• Biochemical Research: Used as a specific inhibitor of protein synthesis to study ribosomal function and translation mechanisms in prokaryotic and eukaryotic systems.
• Antibiotic Mechanism Studies: Serves as a reference standard in research investigating the mode of action and resistance pathways of nucleoside antibiotics.
• Cell Biology: Employed in experiments to selectively inhibit cellular protein production, allowing for the study of gene expression and protein turnover.
• Microbiology: Used in research to understand bacterial response to translation-targeting antimicrobial agents.
• Pharmaceutical Development: Acts as a lead compound or reference molecule in early-stage discovery programs for novel antimicrobial agents.
• Academic & Institutional Labs: A key reagent for universities and research institutes conducting fundamental research in molecular biology and biochemistry.

Basic Information

Product Name	Gougerotin
CAS No.	2096-42-6
Molecular Formula	C₁₂H₁₈N₆O₆
Molecular Weight	342.31 g/mol
Synonyms	Gougerotin; Antibiotic 452; NSC 82116; 4-Amino-1-[4-amino-2-oxo-1(2H)-pyrimidinyl]-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid; 1-(4-Amino-2-oxopyrimidin-1-yl)-4-amino-1,2,3,4-tetradeoxy-β-D-erythro-hex-2-enopyranuronic acid
EINECS	218-246-7

Quality Control

Our Gougerotin is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is subjected to comprehensive analytical testing, including identification by spectroscopic methods and purity assessment by HPLC. A Certificate of Analysis (COA) detailing specific results is provided with every shipment to guarantee traceability and compliance with your research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be kept under anhydrous conditions. For long-term storage, consider storing desiccated at -20°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.