Description

Hexamethonium Tartrate is a quaternary ammonium salt widely recognized for its potent ganglionic blocking activity. This compound is a critical research-grade chemical for investigating autonomic nervous system functions and serves as a key reference standard in pharmacological studies. It is essential for pharmaceutical R&D, academic research, and analytical laboratories focused on neurochemistry and cardiovascular physiology.

Application

• Pharmacological Research: Primarily used as a selective nicotinic acetylcholine receptor (nAChR) antagonist in autonomic ganglia for studying neurotransmission and blood pressure regulation.
• Reference Standard: Serves as a high-purity analytical standard in HPLC, LC-MS, and other chromatographic methods for quality control and method validation.
• Biochemical Assays: Employed in in vitro and ex vivo tissue bath experiments to block ganglionic transmission and study sympathetic and parasympathetic pathways.
• Academic & Educational Use: A fundamental tool in university teaching labs for demonstrating principles of autonomic pharmacology and neuropharmacology.
• Pharmaceutical Development: Used in early-stage drug discovery for target validation and screening compounds that interact with the cholinergic system.

Basic Information

Product Name	Hexamethonium Tartrate
CAS No.	2079-78-9
Molecular Formula	C16H38N2O12
Molecular Weight	450.49 g/mol
Synonyms	Hexamethonium Bitartrate; Hexameton Tartrate; 1,6-Hexanediaminium, N,N,N,N',N',N'-hexamethyl-, (2R,3R)-2,3-dihydroxybutanedioate (1:2); Esametonio Tartrate; Hexamethonium Di-tartrate; Hexamethylhexamethylenediammonium Tartrate; Vegolysen Tartrate
EINECS	218-197-2

Quality Control

Our Hexamethonium Tartrate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC, Titration), and specific tests for related substances and residual solvents, to ensure it meets stringent research-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability for your critical research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after use to prevent moisture absorption, which can affect stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (Titration)	Conforms
Assay (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Total impurities ≤2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.