Description

3-(Pentafluorophenyl)Propionyl Chloride is a high-purity, reactive organofluorine building block essential for advanced chemical synthesis. This compound matters for its role as a key acylating agent, enabling the efficient introduction of the pentafluorophenylpropionyl group into target molecules. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries for creating novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring fluorinated aromatic moieties to enhance metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides where the pentafluorophenyl group can improve product efficacy and environmental profile.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorinated components in electronic display materials, leveraging the properties of fluorine to tune electronic characteristics and stability.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing material properties such as chemical resistance, thermal stability, and surface characteristics.
• Peptide & Protein Research: Acts as an acylating agent for modifying amino acids or peptides, useful in bioconjugation and probe development for biochemical studies.
• Cross-coupling Reagent: Functions as an electrophile in various metal-catalyzed cross-coupling reactions to form carbon-carbon bonds in complex molecule assembly.

Basic Information

Product Name	3-(Pentafluorophenyl)Propionyl Chloride
CAS No.	2063-40-3
Molecular Formula	C9H4ClF5O
Molecular Weight	258.57 g/mol
Synonyms	Pentafluorophenylpropionyl Chloride; 3-(Perfluorophenyl)propionyl Chloride; 3-(Pentafluorophenyl)propanoyl Chloride; 3,4,5,6,7-Pentafluorohydrocinnamoyl Chloride; β-(Pentafluorophenyl)propionyl Chloride; 2063-40-3; Pentafluorohydrocinnamoyl chloride
EINECS	Contact for details

Quality Control

Our 3-(Pentafluorophenyl)Propionyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, containers must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.