Description

Rac Guaifenesin Cyclic Carbonate CAS NO 2049-21-0 is a chemically modified derivative of guaifenesin, designed to offer enhanced stability and controlled-release properties. This compound serves as a key pharmaceutical intermediate, primarily utilized in the development of advanced cough suppressant and expectorant formulations. It is essential for manufacturers in the pharmaceutical and fine chemical sectors seeking to improve drug delivery systems and product performance.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of modern, long-acting expectorant and antitussive (cough suppressant) APIs.
• Controlled-Release Drug Formulations: Its cyclic carbonate structure is leveraged to create prodrugs or polymers that enable sustained and targeted release of guaifenesin.
• Respiratory Medication R&D: Used in research and development of new therapeutic agents for managing bronchitis, asthma, and other respiratory conditions with mucus congestion.
• Polymer Synthesis: Acts as a monomer or modifying agent for synthesizing biodegradable polymers with potential medical applications.
• Fine Chemical Synthesis: Serves as a versatile synthon in organic chemistry for introducing functional groups or creating novel molecular architectures.

Basic Information

Product Name	Rac Guaifenesin Cyclic Carbonate
CAS No.	2049-21-0
Molecular Formula	C13H16O6
Molecular Weight	268.26 g/mol
Synonyms	Guaifenesin Cyclic Carbonate; Guaiphenesin Cyclic Carbonate; 3-(2-Methoxyphenoxy)-1,2-propanediol Cyclic Carbonate; rac-Guaifenesin Carbonate; (±)-Guaifenesin Cyclic Carbonate; 1,2-Propanediol, 3-(2-methoxyphenoxy)-, cyclic carbonate; Glyceryl Guaiacolate Cyclic Carbonate
EINECS	Contact for details

Quality Control

Our Rac Guaifenesin Cyclic Carbonate is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets stringent specifications for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and excessive heat.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.