Description

(3α,5β)-Pregnane-3,20,21-Triol is a high-purity steroid derivative, specifically a pregnane triol, that serves as a critical intermediate in advanced pharmaceutical synthesis and biochemical research. Its defined stereochemistry and functional groups make it a valuable building block for developing steroid-based therapeutics and reference standards. This compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors who require high-quality, well-characterized intermediates for complex synthetic pathways and analytical applications.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the production of steroid hormones and related active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a reference standard or substrate in metabolic pathway studies and enzyme inhibition assays.
• Analytical Chemistry: Serves as a high-purity calibration standard for chromatographic methods (HPLC, GC) in quality control laboratories.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for academic and industrial R&D.
• Metabolite Studies: Utilized in research investigating steroid metabolism and the identification of biological metabolites.

Basic Information

Product Name	(3α,5β)-Pregnane-3,20,21-Triol
CAS No.	2041-77-2
Molecular Formula	C21H36O3
Molecular Weight	336.51 g/mol
Synonyms	5β-Pregnane-3α,20α,21-triol; 3α,20α,21-Trihydroxy-5β-pregnane; 20α,21-Dihydroxypregnanolone; Allopregnanetriol; (3α,5β,20α)-Pregnane-3,20,21-triol; 5β-Pregnan-3α,20α,21-triol; Urocortisol metabolite
EINECS	Contact for details

Quality Control

Our (3α,5β)-Pregnane-3,20,21-Triol is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification (IR, NMR), purity assay (HPLC), and control of related substances, to ensure it meets exacting standards for research and synthesis. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Specific Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.