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9-Arabinofuranosyladenine CAS NO 2006-02-2


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CAS No.:2006-02-2

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

9-Arabinofuranosyladenine is a nucleoside analog and a key intermediate in the synthesis of various antiviral and anticancer agents. This compound matters significantly for its role in pharmaceutical research and development, particularly in the creation of modified nucleosides that target viral polymerases and cellular enzymes. It is primarily needed by pharmaceutical manufacturers, biotechnology research laboratories, and academic institutions engaged in medicinal chemistry and drug discovery programs.

Application

  • Pharmaceutical Intermediate: A critical building block for the synthesis of antiviral and anticancer nucleoside analogs.
  • Biochemical Research: Used as a substrate or inhibitor in enzymatic studies involving polymerases and nucleoside-metabolizing enzymes.
  • Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
  • Antiviral Agent Development: Investigated for its potential activity and as a precursor for compounds targeting herpesviruses and other DNA viruses.
  • Labeled Compound Synthesis: Used in the preparation of isotopically labeled (e.g., 13C, 15N) nucleosides for metabolic tracing and pharmacokinetic studies.
  • Academic & Institutional Research: Employed in university and institutional labs for fundamental research in nucleic acid chemistry and biology.

Basic Information

Product Name 9-Arabinofuranosyladenine
CAS No. 2006-02-2
Molecular Formula C10H13N5O4
Molecular Weight 267.24 g/mol
Synonyms 9-β-D-Arabinofuranosyladenine; Ara-A; Vidarabine (related prodrug); Spongoadenosine; Adenine Arabinoside; 9-(β-D-Arabinofuranosyl)-9H-purin-6-amine; 6-Amino-9-β-D-arabinofuranosyl-9H-purine
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Quality Control

Our 9-Arabinofuranosyladenine is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR, and tests for residual solvents and moisture. We provide Certificates of Analysis (COA) with detailed results for all release specifications, ensuring traceability and compliance with your research or cGMP starting material requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to reference spectrum
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥98.0%
Water Content (KF) ≤2.0%
Residual Solvents (GC) Complies with ICH guidelines
Heavy Metals ≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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