Description

8-Methoxypsoralen is a naturally occurring furocoumarin derivative, also known as xanthotoxin, valued for its potent photosensitizing properties. This compound is a critical active pharmaceutical ingredient (API) and a key intermediate in the synthesis of specialized photochemotherapeutic agents. It is essential for manufacturers and research institutions in the pharmaceutical, cosmetic, and life science sectors requiring high-purity, bioactive molecules for advanced applications.

Application

• Pharmaceutical API: Primary active ingredient in prescription medications for the treatment of skin conditions like vitiligo, psoriasis, and cutaneous T-cell lymphoma (CTCL), used in conjunction with UVA light (PUVA therapy).
• Cosmetic & Dermatological Research: Used in R&D for studying melanogenesis, skin pigmentation disorders, and developing phototherapeutic and depigmentation formulations.
• Biochemical Research: Serves as a standard and reagent in photobiology and photochemistry studies, particularly for investigating DNA cross-linking and cell cycle effects under UV light.
• Agricultural & Botanical Studies: Employed in plant science research due to its natural occurrence in plants like Ammi majus, studying plant defense mechanisms and biosynthesis pathways.
• Reference Standard: Critical as a high-purity certified reference material (CRM) for analytical method development, validation, and quality control in pharmaceutical laboratories.

Basic Information

Product Name	8-Methoxypsoralen
CAS No.	298-81-7
Molecular Formula	C12H8O4
Molecular Weight	216.19 g/mol
Synonyms	Xanthotoxin; Methoxsalen; 8-MOP; 9-Methoxy-7H-furo[3,2-g][1]benzopyran-7-one; Ammoidin; 8-Methoxyfuro[3,2-g]chromen-7-one; 8-Methoxy-7H-furo[3,2-g]chromen-7-one
EINECS	206-066-6

Quality Control

Our 8-Methoxypsoralen is manufactured under strict quality management systems. Each batch is subjected to comprehensive analytical testing, including HPLC for purity, IR and NMR for identification, and residual solvent analysis, to ensure it meets stringent pharmaceutical-grade specifications. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with relevant standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.