Description

Proparacaine is a potent, fast-acting local anesthetic belonging to the ester class of amino benzoate compounds. It is primarily valued for its rapid onset of action and effectiveness in ophthalmic procedures, providing critical pain management and patient comfort. This high-purity active pharmaceutical ingredient (API) is essential for manufacturers in the pharmaceutical and ophthalmic industries developing topical anesthetic solutions and diagnostic agents.

Application

• Ophthalmic Anesthesia: Primary use as a topical anesthetic for eye examinations, tonometry, and minor surgical procedures like corneal suture removal.
• Pharmaceutical Formulations: Key active ingredient in prescription and over-the-counter (OTC) ophthalmic solutions and drops.
• Diagnostic Aid: Used to anesthetize the cornea prior to contact tonometry or other diagnostic tests that require patient cooperation.
• Veterinary Medicine: Application in veterinary ophthalmology for diagnostic and minor surgical procedures in animals.
• Research & Development: Serves as a reference standard and building block in pharmacological research for studying local anesthetic mechanisms and developing new analogs.

Basic Information

Product Name	Proparacaine
CAS No.	298-50-0
Molecular Formula	C16H26N2O3
Molecular Weight	294.39 g/mol
Synonyms	Proparacaine Hydrochloride (common salt form); Ophthalme; Alcaine; AK-Taine; Paracaine; 2-(Diethylamino)ethyl 3-amino-4-propoxybenzoate; Proxymetacaine; Proparacainum; UNII-4Y5P7SBB9J
EINECS	206-058-8

Quality Control

Our Proparacaine is manufactured under strict quality management systems to ensure it meets the stringent requirements for pharmaceutical actives. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling. Certificates of Analysis (COA) confirming compliance with relevant specifications, including potential USP monograph standards, are provided to guarantee consistent quality and traceability for your formulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.