Description

2-Chloroadenosine is a purine nucleoside analog of significant interest in biochemical and pharmaceutical research. This compound serves as a crucial intermediate and a key pharmacophore for developing novel therapeutic agents, particularly in the fields of oncology and cardiology. It is primarily utilized by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers engaged in nucleoside chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of adenosine receptor agonists and antagonists for drug discovery.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies related to adenosine metabolism and signaling pathways.
• Cardiovascular Research: Investigated for its potential effects on heart function and vascular tone due to its structural similarity to adenosine.
• Oncology Research: Serves as a precursor for the development of nucleoside-based chemotherapeutic agents and targeted therapies.
• Neurological Studies: Employed in research exploring adenosine's role in neuroprotection, sleep regulation, and seizure activity.
• Reference Standard: Used as an analytical standard in HPLC and LC-MS methods for quality control and metabolic studies.

Basic Information

Product Name	2-Chloroadenosine
CAS No.	246-77-0
Molecular Formula	C10H12ClN5O4
Molecular Weight	301.69 g/mol
Synonyms	2-Chloro-9-β-D-ribofuranosyladenine; 2-Cl-Ado; 2-Chloroadenosine; 2-Chloro-9-β-D-ribofuranosyl-9H-purin-6-amine; Adenosine, 2-chloro-; 2-Chloro-adenosine; 2-Chloro-9-(β-D-ribofuranosyl)adenine
EINECS	246-077-0

Quality Control

Our 2-Chloroadenosine is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting the specific results for that lot.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.