Description

6-Amino-3-Iodo-4-Methoxy-1-(β-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine is a sophisticated nucleoside analog with a unique pyrazolopyrimidine scaffold, designed for advanced research and development. This compound is of significant interest for its potential as a key synthetic intermediate or a pharmacologically active scaffold in medicinal chemistry programs. It is primarily utilized by research scientists and process development chemists in the pharmaceutical and biotechnology sectors. The specific structural features, including the ribofuranosyl and iodo substituents, make it a valuable building block for probing biological mechanisms and developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel nucleoside-based drug candidates targeting viral infections or oncology.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and related pathways.
• Medicinal Chemistry: Acts as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity against biological targets.
• Antiviral Agent Development: Explored for its potential activity against viruses that utilize nucleoside analogs in their replication cycle.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for complex nucleoside derivatives under GMP or non-GMP conditions.
• Academic Research: Utilized in university and institutional labs for fundamental studies in organic synthesis and chemical biology.

Basic Information

Product Name	6-Amino-3-Iodo-4-Methoxy-1-(β-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine
CAS No.	1997362-11-4
Molecular Formula	C11H14IN5O5
Molecular Weight	423.16 g/mol
Synonyms	6-Amino-3-iodo-4-methoxy-1-β-D-ribofuranosyl-1H-pyrazolo[3,4-d]pyrimidine; 1-(β-D-Ribofuranosyl)-6-amino-3-iodo-4-methoxy-1H-pyrazolo[3,4-d]pyrimidine; 3-Iodo-6-amino-4-methoxy-1-(β-D-ribofuranosyl)pyrazolo[3,4-d]pyrimidine; Iodinated Ribofuranosyl Pyrazolopyrimidine; CAS 1997362-11-4
EINECS	Contact for details

Quality Control

Our 6-Amino-3-Iodo-4-Methoxy-1-(β-D-Ribofuranosyl)-1H-Pyrazolo[3,4-D]Pyrimidine is produced under strict quality management systems to ensure batch-to-batch consistency and high purity for research applications. We employ advanced analytical techniques, including HPLC, NMR, and mass spectrometry, for comprehensive characterization and purity verification. A detailed Certificate of Analysis (COA) is provided with each batch, documenting identity, purity, and impurity profiles. For custom synthesis or specific grade requirements, our technical team is available to discuss tailored specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use to prevent degradation. For long-term storage, consider storing at -20°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.