Description

Tak-659 (Hydrochloride) is a potent and selective small molecule inhibitor targeting specific kinase pathways. This high-purity compound is essential for advancing research and development in oncology and immunology. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions for drug discovery, target validation, and preclinical studies.

Application

• Drug Discovery & Development: Core component for screening and lead optimization in oncology research programs.
• Biochemical & Cellular Assays: Used as a reference standard and active agent in high-throughput screening (HTS) and mechanism-of-action studies.
• Preclinical Research: Critical for in vitro and in vivo studies to evaluate efficacy, pharmacokinetics, and safety profiles.
• Target Validation: A key tool compound for investigating specific signaling pathways and their role in disease progression.
• Chemical Biology: Employed in proteomics and functional genomics to study kinase-mediated cellular processes.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control.

Basic Information

Product Name	Tak-659 (Hydrochloride)
CAS No.	1952251-28-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	TAK-659 HCl; TAK659 Hydrochloride; Sapanisertib Hydrochloride (Note: Verify specific synonymy); N-[3-[5-(4-Acetylpiperazin-1-yl)-1H-benzimidazol-2-yl]phenyl]acetamide hydrochloride; Kinase Inhibitor TAK-659 HCl; Research Compound 1952251-28-3
EINECS	Contact for details

Quality Control

Our Tak-659 (Hydrochloride) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. All materials are characterized using advanced analytical techniques including HPLC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry, cool place. The product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.