Description

5-o-Dmt-2-Fluoro-2-Deoxyinosine is a fluorinated nucleoside analog, a key building block in advanced pharmaceutical research and development. This modified nucleoside is valued for its role in the synthesis of novel antiviral and anticancer agents, where its structural modifications can enhance metabolic stability and target binding affinity. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers focused on nucleotide-based therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of experimental antiviral and anticancer nucleotide analogs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies to investigate nucleotide metabolism and polymerase activity.
• Pro-drug Development: Serves as a key component in the design of nucleotide pro-drugs aimed at improving cellular uptake and bioavailability.
• Antisense Oligonucleotide Synthesis: Employed in the creation of modified oligonucleotides for therapeutic and diagnostic applications.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies to optimize pharmacological properties.

Basic Information

Item	Details
Product Name	5-o-Dmt-2-Fluoro-2-Deoxyinosine
CAS No.	1951424-83-1
Molecular Formula	C22H23FN4O6
Molecular Weight	458.44 g/mol
Synonyms	2'-Fluoro-2'-deoxy-5-O-(4,4'-dimethoxytrityl)inosine; 2'-F-5'-O-DMT-inosine; 5'-O-Dimethoxytrityl-2'-fluoro-2'-deoxyinosine; 2'-Fluoro-5'-O-(4,4'-dimethoxytriphenylmethyl)-2'-deoxyinosine; 2'-F-dI(DMT); 2'-Fluoro-2'-deoxyinosine 5'-O-DMT ether; 1951424-83-1
EINECS	Contact for details

Quality Control

Our 5-o-Dmt-2-Fluoro-2-Deoxyinosine is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to cGMP guidelines for the production of pharmaceutical intermediates, ensuring traceability and documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.