Description

5-Bromo-2-Chloroisonicotinoyl Chloride is a high-purity, multi-functional chemical building block essential for advanced organic synthesis. Its reactive acid chloride group and halogenated pyridine core make it a critical intermediate for constructing complex molecular architectures with precision. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and material science sectors for developing novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and antiviral drug discovery.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis.
• Material Science Research: Employed in the development of organic electronic materials, metal-organic frameworks (MOFs), and functional polymers.
• Custom Synthesis & Contract Manufacturing: A vital reagent for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving global clients.
• Academic & Industrial R&D: Used in research laboratories for methodological studies and the exploration of new chemical reactions and pathways.

Basic Information

Product Name	5-Bromo-2-Chloroisonicotinoyl Chloride
CAS No.	1935952-61-6
Molecular Formula	C7H2BrCl2NO
Molecular Weight	274.91 g/mol
Synonyms	5-Bromo-2-chloroisonicotinic acid chloride; 5-Bromo-2-chloro-4-pyridinecarbonyl chloride; 2-Chloro-5-bromoisonicotinoyl chloride; 4-Pyridinecarbonyl chloride, 5-bromo-2-chloro-; Isonicotinoyl chloride, 5-bromo-2-chloro-
EINECS	Contact for details

Quality Control

Every batch of 5-Bromo-2-Chloroisonicotinoyl Chloride is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistent lot-to-lot quality. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent decomposition. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.