Description

Olutasidenib (Synonyms: Ft-2102) CAS NO 1887014-12-1 is a potent and selective small molecule inhibitor of isocitrate dehydrogenase 1 (IDH1) with the R132H mutation. This compound is of significant value for targeted cancer therapy research and development, specifically for cancers driven by this specific genetic alteration. It is primarily required by pharmaceutical R&D teams, contract research organizations (CROs), and academic institutions focused on oncology, hematology, and precision medicine.

Application

• Pharmaceutical R&D: Key intermediate or active pharmaceutical ingredient (API) in the development of targeted therapies for IDH1-mutant cancers.
• Preclinical Research: Used in in vitro and in vivo studies to investigate the efficacy and mechanism of action of IDH1 inhibition.
• Biochemical Assay Development: Serves as a reference standard or inhibitor in high-throughput screening (HTS) and enzymatic assays targeting mutant IDH1.
• Oncology Biomarker Studies: Utilized in research exploring the relationship between IDH1 mutation status and therapeutic response.
• Academic Research: Fundamental tool for universities and research institutes studying cancer metabolism, epigenetics, and signal transduction pathways.
• Process Chemistry & Scale-Up: Sourced by chemical development teams for route scouting, optimization, and the production of non-GMP or GMP batches.

Basic Information

Product Name	Olutasidenib
CAS No.	1887014-12-1
Molecular Formula	C23H17F3N6O2
Molecular Weight	466.42 g/mol
Synonyms	FT-2102; FT2102; Olutasidenib (USAN); (S)-N-((1-(6-Chloro-2-fluorophenyl)ethyl)-6-(1-hydroxy-2-methylpropan-2-yl)-1-methyl-2-oxo-1,2-dihydropyrido[2,3-d]pyrimidine-7-carboxamide; Rezlidhia; IDH1 Inhibitor FT-2102
EINECS	Contact for details

Quality Control

Our Olutasidenib is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and comprehensive identification and impurity profiling. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with research-grade specifications. We support development with regulatory starting material (RSM) documentation packages.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere (e.g., nitrogen or argon) after opening to maintain stability and purity. Keep container tightly sealed in a desiccator when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥98.0%
Chiral Purity (Chiral HPLC)	≥99.0% ee
Water Content (KF)	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Heavy Metals	<10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.