Description

3-Methyl-5-(Pentafluorosulfur)Benzyl Alcohol is a high-value fluorinated aromatic building block characterized by the presence of a pentafluorosulfanyl (SF5) group. This compound matters for its unique combination of high lipophilicity, metabolic stability, and strong electron-withdrawing properties imparted by the SF5 moiety, making it a sought-after intermediate in advanced synthesis. It is primarily needed by R&D and process development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients with enhanced performance profiles.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and oncology.
• Agrochemical Active Ingredient Synthesis: Used to construct novel herbicides, fungicides, and insecticides where the SF5 group improves weatherfastness and biological activity.
• Advanced Material Science: Serves as a monomer or precursor for specialty polymers, liquid crystals, and electronic materials requiring specific dielectric and stability properties.
• Organic Synthesis Building Block: Employed in cross-coupling reactions, nucleophilic substitutions, and oxidation reactions to introduce the benzyl alcohol and SF5 functionalities into complex molecules.
• Ligand and Catalyst Development: Useful for synthesizing novel chiral ligands or metal-organic frameworks (MOFs) for asymmetric catalysis and separation technologies.

Basic Information

Product Name	3-Methyl-5-(Pentafluorosulfur)Benzyl Alcohol
CAS No.	1858256-52-6
Molecular Formula	C8H7F5OS
Molecular Weight	246.20 g/mol
Synonyms	(3-Methyl-5-(pentafluoro-λ6-sulfanyl)phenyl)methanol; 5-(Hydroxymethyl)-1-methyl-3-(pentafluorosulfanyl)benzene; 3-Methyl-5-SF5-Benzyl Alcohol; 3-Methyl-5-(SF5)Benzyl Alcohol; 1-Methyl-3-(pentafluorosulfanyl)-5-(hydroxymethyl)benzene; α-(3-Methyl-5-pentafluorosulfanylphenyl)methanol
EINECS	Contact for details

Quality Control

Our 3-Methyl-5-(Pentafluorosulfur)Benzyl Alcohol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications such as assay (HPLC), impurity profile, and physical characteristics are provided and available upon request to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.