Description

Pf-739 CAS NO 1852452-14-2 is a high-purity, specialized chemical compound designed for advanced research and development applications. Its precise molecular structure makes it a critical intermediate and building block in the synthesis of novel active pharmaceutical ingredients (APIs) and other fine chemicals. This product is essential for pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of investigational new drugs and active pharmaceutical ingredients (APIs).
• Drug Discovery Research: Used in medicinal chemistry for the design and optimization of novel therapeutic candidates.
• Process Chemistry Development: Serves as a critical reagent in scaling up synthetic routes from laboratory to pilot plant scale.
• Bioconjugation Chemistry: Potential utility in the development of antibody-drug conjugates (ADCs) and other targeted therapies.
• Chemical Biology Probes: Can be utilized to create molecular probes for studying biological pathways and target engagement.
• Academic & Institutional Research: Supports fundamental chemical research in universities and government laboratories.

Basic Information

Product Name	Pf-739
CAS No.	1852452-14-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	PF-739; PF 739; 1852452-14-2; (S)-2-((S)-2-(2-(2,6-Dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)pyrrolidin-1-yl)acetic acid; PROTAC-based compound; Cereblon ligand derivative; E3 ligase ligand.
EINECS	Contact for details

Quality Control

Our Pf-739 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity determination and NMR/LC-MS for structural confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes. We adhere to cGMP principles where applicable to support our clients' regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original sealed container to prevent degradation. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.