Description

5-Vinylcytidine is a modified nucleoside analog of cytidine, featuring a vinyl group at the 5-position of the cytosine base. This structural modification is critical for its role as a key building block in the synthesis of advanced oligonucleotides, enabling precise biochemical research and therapeutic development. It is primarily utilized by researchers and manufacturers in the fields of pharmaceutical development, molecular biology, and diagnostic probe synthesis.

Application

• Oligonucleotide Synthesis: A crucial monomer for the solid-phase synthesis of modified RNA and DNA strands.
• Antisense Therapy Development: Used in creating therapeutic oligonucleotides designed to target specific RNA sequences.
• siRNA and miRNA Research: Incorporated into small interfering RNA (siRNA) and microRNA (miRNA) to enhance stability and specificity.
• Aptamer Development: Serves as a modified base in the selection and optimization of high-affinity nucleic acid aptamers.
• Chemical Biology Probes: Enables the site-specific labeling and functionalization of nucleic acids for imaging and interaction studies.
• Bioconjugation: The vinyl group provides a reactive handle for click chemistry and other bioconjugation strategies.

Basic Information

Product Name	5-Vinylcytidine
CAS No.	1846584-62-0
Molecular Formula	C11H15N3O5
Molecular Weight	269.26 g/mol
Synonyms	5-Vinylcytidine; Cytidine, 5-vinyl-; 1-[(2R,3R,4S,5R)-3,4-Dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-5-vinylpyrimidine-2,4-dione; 5-Vinyl-1-β-D-ribofuranosylcytosine; 5-Vinyl-Cytidine; 5-Vinylcytidine nucleoside
EINECS	Contact for details

Quality Control

Our 5-Vinylcytidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.