Description

2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzoyl Chloride is a high-value, multi-functional aromatic acid chloride intermediate. Its core value lies in its unique trifluoromethyl and fluorine substituents, which are critical for modulating the lipophilicity, metabolic stability, and binding affinity of target molecules. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of advanced active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially those targeting central nervous system (CNS) disorders, oncology, and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the fluorine and trifluoromethyl groups enhance biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for synthesizing fluorinated aromatic compounds used in electronic displays and organic light-emitting diodes.
• Polymer Chemistry: Acts as a monomer or modifier in the production of specialty polymers with enhanced chemical resistance and thermal stability.
• Chemical Research & Development: A versatile reagent for introducing the 2-fluoro-4-methyl-3-(trifluoromethyl)benzoyl moiety into complex molecules during exploratory synthesis.
• Dye & Pigment Intermediate: Employed in the manufacture of high-performance, light-fast fluorinated dyes and pigments.

Basic Information

Product Name	2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzoyl Chloride
CAS No.	1824271-04-6
Molecular Formula	C9H5ClF4O
Molecular Weight	240.58 g/mol
Synonyms	2-Fluoro-4-methyl-3-(trifluoromethyl)benzoyl chloride; 2-Fluoro-α,α,α,4-tetramethylbenzoyl chloride; 3-(Trifluoromethyl)-2-fluoro-4-methylbenzoyl chloride; 2-Fluoro-4-methyl-3-trifluoromethylbenzoyl chloride; Benzoyl chloride, 2-fluoro-4-methyl-3-(trifluoromethyl)-; 1824271-04-6
EINECS	Contact for details

Quality Control

Our 2-Fluoro-4-Methyl-3-(Trifluoromethyl)Benzoyl Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and Karl Fischer titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific customer requirements for research, development, or cGMP manufacturing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent decomposition. Keep away from heat, open flames, and incompatible materials such as strong bases, alcohols, and water.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.