Description

(6-(Allyloxy)-2,3-Difluorophenyl)Methanol is a versatile fluorinated aromatic building block with an allyl ether and a benzylic alcohol functional group. This unique bifunctional structure makes it a critical intermediate for synthesizing advanced pharmaceutical compounds and high-performance specialty materials. It is primarily sought by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in fluorinated drug candidates targeting CNS disorders and oncology.
• Agrochemical Synthesis: Used in the research and production of next-generation herbicides and fungicides, where the difluorophenyl moiety enhances biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a precursor for fluorinated mesogens and electron-transport materials, improving the performance and durability of display technologies.
• Polymer Modification: Employed to introduce photoreactive allyl groups and fluorinated aromatic units into polymer backbones, enhancing material properties like chemical resistance and thermal stability.
• Cross-coupling Reactions: The benzylic alcohol can be activated for Suzuki-Miyaura, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions to create complex biaryl systems.
• Protecting Group Chemistry: The allyloxy group can act as a protective group for phenols or be selectively removed/transformed under mild conditions in multi-step synthetic sequences.

Basic Information

Product Name	(6-(Allyloxy)-2,3-Difluorophenyl)Methanol
CAS No.	1823942-84-2
Molecular Formula	C10H10F2O2
Molecular Weight	200.18 g/mol
Synonyms	2,3-Difluoro-6-(allyloxy)benzyl alcohol; (2,3-Difluoro-6-(prop-2-en-1-yloxy)phenyl)methanol; 1-(Allyloxy)-2,3-difluoro-6-(hydroxymethyl)benzene; Benzyl alcohol, 2,3-difluoro-6-(2-propen-1-yloxy)-; 6-Allyloxy-2,3-difluorobenzyl alcohol
EINECS	Contact for details

Quality Control

Every batch of (6-(Allyloxy)-2,3-Difluorophenyl)Methanol is produced and controlled under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up activities. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is supplied with each shipment, and custom purity grades (e.g., >97%, >98%, >99%) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is moisture-sensitive (hygroscopic); keep the container tightly sealed under an inert atmosphere (nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.