Description

(2-(Benzyloxy)-4,5-Difluorophenyl)Methanol is a specialized fluorinated aromatic building block of significant interest in advanced organic synthesis. Its value lies in its unique molecular structure, which incorporates both a benzyl-protected phenol and difluorinated aromatic ring, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), agrochemicals, and high-performance materials.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides, where the difluorophenyl moiety can enhance biological activity and metabolic stability.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for fluorinated aromatic cores used in electronic display technologies and organic light-emitting diodes (OLEDs).
• Polymer Chemistry: Employed in the synthesis of specialty polymers and resins, where its structure can impart specific thermal or chemical resistance properties.
• Chemical Research & Development: A valuable reagent for method development and exploring new fluorination and coupling reactions in academic and industrial R&D labs.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of client-specific target molecules on a commercial scale.

Basic Information

Product Name	(2-(Benzyloxy)-4,5-Difluorophenyl)Methanol
CAS No.	1823862-22-1
Molecular Formula	C14H12F2O2
Molecular Weight	250.24 g/mol
Synonyms	2-(Benzyloxy)-4,5-difluorobenzyl alcohol; (4,5-Difluoro-2-(phenylmethoxy)phenyl)methanol; 4,5-Difluoro-2-(benzyloxy)benzyl alcohol; 1-(Benzyloxy)-2,3-difluoro-4-(hydroxymethyl)benzene; Benzhydryl alcohol, 4,5-difluoro-2-(phenylmethoxy)-; [2-(Benzyloxy)-4,5-difluorophenyl]methanol
EINECS	Contact for details

Quality Control

Our (2-(Benzyloxy)-4,5-Difluorophenyl)Methanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.