Description

2-[(3-Fluorophenyl)Carbonyl]Piperidine Hydrochloride is a high-purity, advanced pharmaceutical intermediate with the CAS number 1820734-90-4. This compound is a key building block in modern medicinal chemistry, valued for its role in constructing complex molecular scaffolds. It is primarily utilized by research institutions and pharmaceutical manufacturers engaged in the development of new active pharmaceutical ingredients (APIs), particularly within central nervous system (CNS) and oncology research pipelines.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of novel drug candidates, especially those targeting neurological disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• API Development: Serves as a key chiral building block in the multi-step synthesis of complex active pharmaceutical ingredients.
• Chemical Biology Probes: Employed in the development of tool compounds for studying biological pathways and target validation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development.
• Academic Research: Used in university and institutional labs for exploratory synthetic chemistry and pharmacology projects.

Basic Information

Product Name	2-[(3-Fluorophenyl)Carbonyl]Piperidine Hydrochloride
CAS No.	1820734-90-4
Molecular Formula	C12H14FNO • HCl
Molecular Weight	243.70 g/mol (Free base: 207.24 g/mol)
Synonyms	1-(3-Fluorobenzoyl)piperidine hydrochloride; 2-(3-Fluorobenzoyl)piperidine HCl; 3-Fluoro-α-piperidinobenzyl alcohol hydrochloride (tautomer); Piperidine, 2-(3-fluorobenzoyl)-, hydrochloride; 1820734-90-4; 2-(3-Fluorobenzoyl)piperidinium chloride
EINECS	Contact for details

Quality Control

Our 2-[(3-Fluorophenyl)Carbonyl]Piperidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent control of residual solvents and impurities. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, ensuring compliance with the high standards required for pharmaceutical R&D and cGMP starting material applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	< 20 ppm
Assay (Titration)	97.0% - 103.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.