Description

2'-Deoxy-2'-Fluorocytidine Hydrate is a fluorinated nucleoside analog of significant interest in advanced pharmaceutical research and development. This modified cytidine derivative is valued for its role as a key building block and intermediate in the synthesis of novel therapeutic agents, particularly in the antiviral and anticancer fields. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of nucleotide-based drugs and diagnostic probes.

Application

• Pharmaceutical Intermediate: Critical building block for the synthesis of antiviral and anticancer nucleotide analogs.
• Antiviral Drug Research: Used in the development of novel therapeutics targeting RNA viruses, where fluorinated nucleosides can act as chain terminators.
• Oncology Research: Serves as a precursor in the creation of chemotherapeutic agents that interfere with DNA/RNA synthesis in rapidly dividing cells.
• Biochemical Research: Employed in enzymatic studies and as a substrate analog to investigate nucleic acid metabolism and polymerase mechanisms.
• Diagnostic Probe Development: Utilized in the synthesis of labeled nucleotides for molecular diagnostics and imaging techniques.
• Pre-clinical & Clinical Trial Material: Supplied as a high-purity intermediate for the production of Active Pharmaceutical Ingredients (APIs) under development.

Basic Information

Product Name	2'-Deoxy-2'-Fluorocytidine Hydrate
CAS No.	1820580-34-4
Molecular Formula	C9H12FN3O4 · xH2O
Molecular Weight	245.21 g/mol (Anhydrous basis)
Synonyms	2'-Fluoro-2'-deoxycytidine Hydrate; 2'-F-dCyd Hydrate; 1-(2-Deoxy-2-fluoro-β-D-ribofuranosyl)cytosine Hydrate; 2'-Fluorocytidine, 2'-deoxy-, Hydrate; 2'-Deoxy-2'-fluorocytidine monohydrate; FCyd Hydrate; 2F-dC Hydrate
EINECS	Contact for details

Quality Control

Our 2'-Deoxy-2'-Fluorocytidine Hydrate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity, suitable for research and pharmaceutical applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards and can support development projects requiring material manufactured under GMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥98.0%
Water Content (KF)	≤5.0%
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤2.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.