Description

5-Bromo-2-Fluorobiphenyl is a high-purity fluorinated biphenyl derivative, a crucial building block in advanced organic synthesis. Its value lies in its unique halogenated structure, which facilitates the development of complex molecules with tailored properties. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries seeking to innovate in drug discovery and specialty chemical production.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of active pharmaceutical ingredients (APIs), particularly for compounds targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, where the fluorine and bromine substituents enhance biological activity and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a core structural unit in the synthesis of advanced electronic materials for displays and lighting due to its rigid biphenyl framework and halogen functionalities.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to construct more complex biaryl systems.
• Organic Light-Emitting Diodes (OLEDs): Acts as a precursor for electron-transport materials and host materials in emissive layers.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and novel compound libraries.

Basic Information

Product Name	5-Bromo-2-Fluorobiphenyl
CAS No.	1809168-63-5
Molecular Formula	C12H8BrF
Molecular Weight	251.10 g/mol
Synonyms	2-Fluoro-5-bromobiphenyl; [1,1'-Biphenyl]-2-fluoro-5-bromo; 5-Bromo-2-fluorobiphenyl; 2-Fluoro-5-phenylbromobenzene; 5-Bromo-2-fluoro-1,1'-biphenyl; Biphenyl, 5-bromo-2-fluoro-; 1809168-63-5
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Fluorobiphenyl is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide a detailed Certificate of Analysis (COA) with every shipment, guaranteeing traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.