Description

3-Bromo-5-Chloro-2-Fluorobenzyl Alcohol is a high-purity, multi-halogenated benzyl alcohol derivative that serves as a critical building block in advanced organic synthesis. Its unique halogen substitution pattern makes it a valuable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical and agrochemical sectors for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders and infectious diseases.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging its halogenated structure for bioactivity.
• Ligand & Catalyst Precursor: Serves as a starting material for the preparation of specialized ligands used in transition metal catalysis and cross-coupling reactions.
• Material Science: Employed in the synthesis of functionalized polymers and liquid crystals where the introduction of halogen and alcohol groups modifies material properties.
• Chemical Biology Probe Synthesis: Utilized to create tagged molecules for studying biological pathways and protein interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of bespoke compounds on a commercial scale.

Basic Information

Product Name	3-Bromo-5-Chloro-2-Fluorobenzyl Alcohol
CAS No.	1809161-65-6
Molecular Formula	C7H5BrClFO
Molecular Weight	239.47 g/mol
Synonyms	(3-Bromo-5-chloro-2-fluorophenyl)methanol; 2-Fluoro-3-bromo-5-chlorobenzyl alcohol; 1-(Bromomethyl)-3-chloro-5-fluorobenzene (tautomeric form); α-Hydroxymethyl-3-bromo-5-chloro-2-fluorobenzene; Benzenemethanol, 3-bromo-5-chloro-2-fluoro-; 3-Bromo-5-chloro-2-fluoro-benzenemethanol
EINECS	Contact for details

Quality Control

Every batch of 3-Bromo-5-Chloro-2-Fluorobenzyl Alcohol is manufactured under strict quality management systems and undergoes rigorous analytical testing to ensure identity, purity, and consistency. Our standard grade typically meets a purity specification of ≥97% (by HPLC), with custom purities up to 99%+ available. A comprehensive Certificate of Analysis (COA) detailing assay, impurity profile, and physical characteristics is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.