Description

(Abl-053) CAS NO 1808287-83-3 is a high-purity, advanced pharmaceutical intermediate designed for research and development in targeted drug discovery. This compound is critical for medicinal chemists working on novel therapeutic agents, particularly in oncology and other disease areas requiring precise molecular scaffolds. It is primarily utilized by pharmaceutical R&D laboratories, biotechnology companies, and academic research institutions engaged in the synthesis of innovative active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of novel small-molecule drug candidates.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds for potency and selectivity.
• Oncology Drug Development: A crucial precursor in the synthesis of targeted cancer therapies, including kinase inhibitors.
• Preclinical Studies: Employed to produce compounds for in vitro and in vivo pharmacological and toxicological evaluation.
• Process Chemistry: Supports route scouting and optimization for scalable API manufacturing processes.
• Chemical Biology Probes: Can be utilized to develop tool compounds for investigating specific biological pathways and target validation.

Basic Information

Product Name	(Abl-053)
CAS No.	1808287-83-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Abl-053; 1808287-83-3; (Abl-053) CAS NO 1808287-83-3; Abl053; ABL 053; ABL053; 4-(4-Methylpiperazin-1-yl)aniline derivative (example IUPAC class); Pharmaceutical Intermediate Abl-053
EINECS	Contact for details

Quality Control

Our (Abl-053) is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling using advanced techniques like HPLC and LC-MS. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep the container sealed to protect from moisture. For long-term storage, consider inert gas purging.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 99.0%
Related Substances (HPLC)	Individual impurity ≤ 0.5% Total impurities ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.