Description

(2-Fluoro-4-Methyl-5-Nitro-Phenyl)-Methanol is a specialized fluorinated nitroaromatic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a fluorinated aromatic ring and a nitro group, makes it a valuable precursor for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the development of new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel drug candidates, particularly those targeting CNS disorders and oncology, where the fluorine atom can enhance metabolic stability and bioavailability.
• Agrochemical Research: Used in the development of next-generation herbicides, fungicides, and pesticides, leveraging the nitro and fluorine substituents for biological activity.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials due to its electron-withdrawing nitro group and potential for further functionalization.
• Dye and Pigment Synthesis: Acts as an intermediate in the production of specialized nitroaromatic dyes and colorants.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring fluorinated nitroaromatic chemistry.

Basic Information

Product Name	(2-Fluoro-4-Methyl-5-Nitro-Phenyl)-Methanol
CAS No.	1806480-23-8
Molecular Formula	C8H8FNO3
Molecular Weight	185.15 g/mol
Synonyms	(2-Fluoro-4-methyl-5-nitrophenyl)methanol; 2-Fluoro-4-methyl-5-nitrobenzenemethanol; 5-Nitro-2-fluoro-4-methylbenzyl alcohol; 1-(Hydroxymethyl)-2-fluoro-4-methyl-5-nitrobenzene; (2-Fluoro-4-methyl-5-nitrophenyl)carbinol; α-Hydroxy-2-fluoro-4-methyl-5-nitrotoluene; Benzenemethanol, 2-fluoro-4-methyl-5-nitro-
EINECS	Contact for details

Quality Control

Every batch of (2-Fluoro-4-Methyl-5-Nitro-Phenyl)-Methanol is manufactured and tested under a strict quality management system. We ensure high purity and batch-to-batch consistency through rigorous analytical protocols, including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.