Description

2'-C-Methyl-6-Methyluridine is a modified nucleoside analog of significant interest in advanced pharmaceutical research and development. This high-purity intermediate is critical for the synthesis of novel antiviral and anticancer therapeutics, particularly those targeting RNA-dependent RNA polymerases. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in nucleoside chemistry. The compound's specific structural modifications make it a valuable building block for probing biological mechanisms and developing next-generation treatments.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of nucleoside-based antiviral and anticancer prodrugs.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving viral polymerases.
• Antiviral Drug Development: Core scaffold for developing therapeutics against RNA viruses, including Hepatitis C Virus (HCV) and other flaviviruses.
• Medicinal Chemistry: Serves as a crucial intermediate for structure-activity relationship (SAR) studies to optimize drug potency and selectivity.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for active pharmaceutical ingredients (APIs).
• Reference Standard: Used as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	2'-C-Methyl-6-Methyluridine
CAS No.	1802937-54-7
Molecular Formula	C11H16N2O6
Molecular Weight	272.25 g/mol
Synonyms	6-Methyl-2'-C-methyluridine; 2'-C-Methyl-6-methyluridine; 1-((2R,3R,4R,5R)-3,4-Dihydroxy-5-(hydroxymethyl)-3-methyltetrahydrofuran-2-yl)-6-methylpyrimidine-2,4(1H,3H)-dione; 2'-C-Me-6-Me-uridine; 2'-C-Methyl-6-methyl-Uridine; Modified Nucleoside Intermediate
EINECS	Contact for details

Quality Control

Our 2'-C-Methyl-6-Methyluridine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research and pharmaceutical applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and tests for residual solvents and moisture. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.